Journal article
Evaluation of novel combined carbogen USPIO (CUSPIO) imaging biomarkers in assessing the antiangiogenic effects of cediranib (AZD2171) in rat C6 gliomas
- Abstract:
-
The recently described combined carbogen USPIO (CUSPIO) magnetic resonance imaging (MRI) method uses spatial correlations in independent imaging biomarkers to assess specific components of tumor vascular structure and function. Our study aimed to evaluate CUSPIO biomarkers for the assessment of tumor response to antiangiogenic therapy. CUSPIO imaging was performed in subcutaneous rat C6 gliomas before and 2 days after treatment with the potent VEGF-signaling inhibitor cediranib (n = 12), or v...
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Bibliographic Details
- Journal:
- International Journal of Cancer
- Volume:
- 131
- Issue:
- 8
- Pages:
- 1854-1862
- Publication date:
- 2012-10-15
- DOI:
- EISSN:
-
1097-0215
- ISSN:
-
0020-7136
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:350941
- UUID:
-
uuid:65e596ef-20fc-418b-8b42-d9a310374a44
- Local pid:
- pubs:350941
- Source identifiers:
-
350941
- Deposit date:
- 2013-11-16
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- Copyright date:
- 2012
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