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Oral versus intravenous antibiotic treatment for bone and joint infections (OVIVA): Study protocol for a randomised controlled trial

Abstract:

Background: Bone and joint infection in adults arises most commonly as a complication of joint replacement surgery, fracture fixation and diabetic foot infection. The associated morbidity can be devastating to patients and costs the National Health Service an estimated £20,000 to £40,000 per patient. Methods: The OVIVA trial is a parallel group, randomised (1:1), un-blinded, non-inferiority trial conducted in thirty hospitals across the UK. Eligible participants are adults (>18 years) with...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s13063-015-1098-y

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Grant:
ealth Technology Assessment project number 11/36/29
Publisher:
BioMed Central Publisher's website
Journal:
Trials Journal website
Volume:
16
Pages:
Article: 583
Publication date:
2015-12-05
DOI:
EISSN:
1745-6215
URN:
uuid:65d52757-9ca6-45f9-ab42-e4ad64afed4c
Source identifiers:
581196
Local pid:
pubs:581196

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