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Do individualized medication effectiveness tests (n-of-1 trials) change clinical decisions about which drugs to use for osteoarthritis and chronic pain?

Abstract:

To assess the impact of individualized medication effectiveness tests (IMETs, or n-of-1 trials), on patients' short-term decision making about medications for chronic pain. Survey evaluation of patients undergoing a double-blind, crossover comparison of drug versus placebo, drug versus drug, or drug versus drug combination using paracetamol and ibuprofen in 3 pairs of treatment periods, randomized within pairs. General practice patients (supplemented by a few from 2 tertiary pain clinics) wit...

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Authors


Nikles, CJ More by this author
Yelland, M More by this author
Glasziou, PP More by this author
Del Mar, C More by this author
Journal:
American journal of therapeutics
Volume:
12
Issue:
1
Pages:
92-97
Publication date:
2005
DOI:
EISSN:
1536-3686
ISSN:
1075-2765
URN:
uuid:65d0e71f-151b-4647-a418-5082f550055e
Source identifiers:
215729
Local pid:
pubs:215729

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