- Abstract:
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DNA origami offers the possibility of developing novel membrane-spanning pores with potential applications in therapeutics and in nanosensors. In this work multiscale molecular dynamics simulation approaches have been employed to understand the dynamics of a DNA nanotube, and of its interaction with lipid bilayer membranes. All-atom simulation studies performed on the DNA nanotube model allowed exploration of its conformational dynamics, and of its interactions with ions and water molecule...
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Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
- Funding agency for:
- Vishal Maingi
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Copyright date:
- 2016
Thesis
DNA nanotubes and their interaction with membranes: insights through multiscale molecular dynamics simulations
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Funding
+ Clarendon Fund and Exeter College SK Pathak Scholarship
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