Reverse genetics of Drosophila brain structure and function.

Journal article

A set of molecular genetic technologies are described, which will have far reaching consequences for the study of brain structure, function and development in Drosophila melanogaster. Site selected mutagenesis (a PCR-based screen for P-element insertion events) allows insertion mutants to be isolated for any cloned gene, and is being used in this laboratory to ask questions about the rolls of particular cellular components in learning and memory. Transposants have been isolated in genes encod...

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Authors: Sentry, J; Goodwin, S; Milligan, C; Duncanson, A; Yang, M

• Publication status: Published
• Journal: Progress in neurobiology
• Volume: 42
• Issue: 2
• Pages: 299-308
• Publication date: 1994-02-01
• DOI: 10.1016/0301-0082(94)90069-8
• EISSN: 1873-5118
• ISSN: 0301-0082
• Language: English
• Keywords: Learning; Gene Expression; Memory; Animals; Brain; Drosophila melanogaster; Mutagenesis, Site-Directed