Journal article
The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor
- Abstract:
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The MITF and SOX10 transcription factors regulate the expression of genes important for melanoma proliferation, invasion and metastasis. Despite growing evidence of the contribution of long noncoding RNAs (lncRNAs) in cancer, including melanoma, their functions within MITF-SOX10 transcriptional programmes remain poorly investigated. Here we identify 245 candidate melanoma associated lncRNAs whose loci are co-occupied by MITF-SOX10 and that are enriched at active enhancer-like regions. Our wor...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.8MB)
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- Publisher copy:
- 10.1371/journal.pgen.1008501
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Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Volume:
- 15
- Issue:
- 12
- Article number:
- e1008501
- Publication date:
- 2019-12-27
- Acceptance date:
- 2019-12-06
- DOI:
- EISSN:
-
1553-7404
- ISSN:
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1553-7390
- Source identifiers:
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1077606
Item Description
- Pubs id:
-
pubs:1077606
- UUID:
-
uuid:6592b477-ee3f-436e-9119-3dc013505198
- Local pid:
- pubs:1077606
- Deposit date:
- 2019-12-13
Terms of use
- Copyright holder:
- Coe et al
- Copyright date:
- 2019
- Notes:
- © 2019 Coe et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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