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Spatial working memory and the brainstem cholinergic innervation to the anterior thalamus

Abstract:

The anteroventral thalamic nucleus (AV) has a role in spatial memory, but the influence of the prominent brainstem cholinergic projection to this region is unknown. Here, spatial memory in a 12-arm radial maze was examined after 0.15 μl bilateral AV infusions of scopolamine. In part one, rats visited six arms singly (the phase 1 arms) and, after a 10 min delay, were allowed free choice to both phase 1 arms and the remaining six baited arms (phase 2 arms). Scopolamine (10 μg) administered duri...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Publisher:
Society for Neuroscience Publisher's website
Journal:
Journal of Neuroscience Journal website
Volume:
5
Issue:
22
Pages:
1922-1928
Publication date:
2002-01-01
Acceptance date:
2001-12-06
EISSN:
1529-2401
ISSN:
0270-6474
Source identifiers:
433382
Keywords:
Pubs id:
pubs:433382
UUID:
uuid:653de381-c07f-490a-8084-5c1643be0ad5
Local pid:
pubs:433382
Deposit date:
2016-05-09

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