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Immunophenotyping of macrophages in human pulmonary tuberculosis and sarcoidosis.

Abstract:

Classic studies of tuberculosis (TB) revealed morphologic evidence of considerable heterogeneity of macrophages (MØs), but the functional significance of this heterogeneity remains unknown. We have used newly available specific antibodies for selected membrane and secretory molecules to examine the phenotype of MØs in situ in a range of South African patients with TB, compared with sarcoidosis. Patients were human immunodeficiency virus-negative adults and children, and the examined biopsy sp...

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Publication status:
Published

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Authors


Stanton, LA More by this author
Fenhalls, G More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School, BHF Centre of Research Excellence
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Journal:
International journal of experimental pathology
Volume:
84
Issue:
6
Pages:
289-304
Publication date:
2003-12-05
DOI:
EISSN:
1365-2613
ISSN:
0959-9673
URN:
uuid:652a0e21-57bc-4f06-92ee-be57381c22b0
Source identifiers:
19553
Local pid:
pubs:19553

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