- Abstract:
-
Constitutive nitric oxide synthases (NOSs) are ubiquitous enzymes that play a pivotal role in the regulation of myocardial function in health and disease. The discovery of both a neuronal NOS (nNOS) and an endothelial NOS (eNOS) isoform in the myocardium and the availability of genetically modified mice with selective eNOS or nNOS gene deletion have been of crucial importance for understanding the role of constitutive nitric oxide (NO) production in the myocardium. eNOS and nNOS are homologou...
Expand abstract - Publisher copy:
- 10.1016/j.yjmcc.2011.09.006
-
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- Journal:
- Journal of Molecular and Cellular Cardiology
- Volume:
- 52
- Issue:
- 2
- Pages:
- 341-350
- Publication date:
- 2012-02-05
- DOI:
- EISSN:
-
1095-8584
- ISSN:
-
0022-2828
- URN:
-
uuid:6511eef3-5bfe-4ebb-8b26-496f6515bbb9
- Source identifiers:
-
313404
- Local pid:
- pubs:313404
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Sub-cellular targeting of constitutive NOS in health and disease
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