Journal article icon

Journal article

A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics.

Abstract:

Methylation of lysine residues on the tails of histone proteins is a major determinant of the transcription state of associated DNA coding regions. The interplay among methylation states and other histone modifications to direct transcriptional outcome is referred to as the histone code. In addition to histone methyltransferases and demethylases which function to modify the methylation state of lysine sidechains, other proteins recognize specific histone methylation marks essentially serving ...

Expand abstract

Actions


Authors


Quinn, Amy M More by this author
Bedford, Mark T More by this author
Espejo, Alexsandra More by this author
Spannhoff, Astrid More by this author
Austin, Christopher P More by this author
Expand authors...
Journal:
Nucleic acids research
Volume:
38
Issue:
2
Pages:
e11
Publication date:
2010
ISSN:
1362-4962
URN:
uuid:6510ab6f-41e9-4004-9dd8-4d441e4e8425
Local pid:
SGC:19897549

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP