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GAT: a simulation framework for testing the association of genomic intervals.

Abstract:

A common question in genomic analysis is whether two sets of genomic intervals overlap significantly. This question arises, for example, when interpreting ChIP-Seq or RNA-Seq data in functional terms. Because genome organization is complex, answering this question is non-trivial.We present Genomic Association Test (GAT), a tool for estimating the significance of overlap between multiple sets of genomic intervals. GAT implements a null model that the two sets of intervals are placed independen...

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Publication status:
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Human Genetics Wt Centre
Role:
Author
Journal:
Bioinformatics (Oxford, England)
Volume:
29
Issue:
16
Pages:
2046-2048
Publication date:
2013-08-05
DOI:
EISSN:
1367-4811
ISSN:
1367-4803
URN:
uuid:64d36f85-2f0a-414c-bab9-ce1b2beb4230
Source identifiers:
407564
Local pid:
pubs:407564

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