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Journal article

Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice

Abstract:

Dyslipidaemia and inflammation are closely interconnected in their contribution to atherosclerosis. In fact, low-density lipoprotein (LDL)-lowering drugs have anti-inflammatory effects. The Canakinumab Antiinflammatory Thrombosis Outcome Study (CANTOS) has shown that interleukin (IL)-1β blockade reduces the incidence of cardiovascular events in patients with previous myocardial infarction and C-reactive protein levels >2 mg/L. These data confirm the connection between lipids and inflammati...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Files:
Publisher copy:
10.1177/2047487318773384

Authors


Tuñón, J More by this author
Badimón, L More by this author
Bochaton-Piallat, M-L More by this author
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Publisher:
SAGE Publisher's website
Journal:
European Journal of Preventive Cardiology Journal website
Volume:
25
Issue:
9
Pages:
948-955
Publication date:
2018-05-14
Acceptance date:
2018-03-31
DOI:
EISSN:
2047-4881
ISSN:
2047-4873
Pubs id:
pubs:853224
URN:
uri:64d1b788-881a-4baa-b720-3ebc6597fe8e
UUID:
uuid:64d1b788-881a-4baa-b720-3ebc6597fe8e
Local pid:
pubs:853224

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