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The potent bisphosphonate ibandronate does not induce myeloma cell apoptosis in a murine model of established multiple myeloma.

Abstract:

Bisphosphonates are effective in the management of bone disease in patients with multiple myeloma and recent reports have suggested that they may also have an anti-tumour activity. In support of this, we have previously demonstrated that bisphosphonates can induce myeloma cell apoptosis in vitro; however, it remains unclear whether this occurs in vivo. We have therefore investigated the effect of the potent bisphosphonate ibandronate in the 5T2MM murine model of established multiple myeloma. ...

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Publication status:
Published

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Journal:
British journal of haematology
Volume:
111
Issue:
1
Pages:
283-286
Publication date:
2000-10-01
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
Source identifiers:
384071
Language:
English
Keywords:
Pubs id:
pubs:384071
UUID:
uuid:64b9dda2-887c-4a6d-af20-e13c7a032ac2
Local pid:
pubs:384071
Deposit date:
2013-11-16

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