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Effects of encapsulated rabbit mesenchymal stem cells on ex vivo expansion of human umbilical cord blood hematopoietic stem/progenitor cells.

Abstract:

The expansion of umbilical cord blood mononuclear cells (UCB MNCs) was investigated in a novel co-culture system by means of encapsulation of rabbit bone marrow (BM) mesenchymal stem cells (MSCs) in alginate beads (Alg beads). Three kinds of media were applied and the experiments lasted for 7 days. The total nucleated cell density was measured every 24 h. Flow cytometric assay for CD34(+) cells and methylcellulose colony assays were carried out at 0, 72 and 168 h. It was found that the encaps...

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Publication status:
Published

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Publisher copy:
10.1080/02652040802193014

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Journal:
Journal of microencapsulation
Volume:
26
Issue:
2
Pages:
130-142
Publication date:
2009-03-05
DOI:
EISSN:
1464-5246
ISSN:
0265-2048
URN:
uuid:64b4af49-3341-4f6a-a05a-e52ba779c401
Source identifiers:
62094
Local pid:
pubs:62094

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