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Targets downstream of Cdk8 in Dictyostelium development.

Abstract:

Background: Cdk8 is a component of the mediator complex which facilitates transcription by RNA polymerase II and has been shown to play an important role in development of Dictyostelium discoideum. This eukaryote feeds as single cells but starvation triggers the formation of a multicellular organism in response to extracellular pulses of cAMP and the eventual generation of spores. Strains in which the gene encoding Cdk8 have been disrupt...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-213x-11-2

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Publisher:
BioMed Central
Journal:
BMC developmental biology More from this journal
Volume:
11
Issue:
1
Pages:
2
Publication date:
2011-01-01
DOI:
EISSN:
1471-213X
ISSN:
1471-213X

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