Journal article
Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points.
- Abstract:
-
Haematopoiesis is the complex developmental process that maintains the turnover of all blood cell lineages. It critically depends on the correct functioning of rare, quiescent haematopoietic stem cells (HSCs) and more numerous, HSC-derived, highly proliferative and differentiating haematopoietic progenitor cells (HPCs). Infection is known to affect HSCs, with severe and chronic inflammatory stimuli leading to stem cell pool depletion, while acute, non-lethal infections exert transient and eve...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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- Files:
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(pdf, 1.1MB)
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- Publisher copy:
- 10.1098/rsob.160038
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Authors
Funding
Biotechnology and Biological Sciences Research Council
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European Research Council
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Bibliographic Details
- Publisher:
- Royal Society Publisher's website
- Journal:
- Open Biology Journal website
- Issue:
- 6
- Publication date:
- 2016-06-22
- Acceptance date:
- 2016-05-27
- DOI:
- ISSN:
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2046-2441
- Pubs id:
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pubs:631089
- URN:
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uri:64a51c0b-6aed-4f7f-a6c5-5d436d2e01cf
- UUID:
-
uuid:64a51c0b-6aed-4f7f-a6c5-5d436d2e01cf
- Local pid:
- pubs:631089
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright holder:
- Vainieri et al.
- Copyright date:
- 2016
- Notes:
- © 2016 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
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