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RD Lawrence Lecture 2009. Old genes, new tricks: learning about blood glucose regulation from naturally occurring genetic variation in humans.

Abstract:

The study of rare monogenic forms of diabetes and pancreatic B-cell dysfunction provides an unrivalled opportunity to link a specific change in gene function with precise cellular consequences and clinical phenotype in humans. Over the past 20 years there has been considerable success in determining the genetic aetiology of a number of rare monogenic forms of diabetes, which has had a significant impact on both our understanding of normal physiology and on translational medicine. The impact o...

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Journal:
Diabetic medicine : a journal of the British Diabetic Association
Volume:
26
Issue:
11
Pages:
1083-1089
Publication date:
2009-11-05
DOI:
EISSN:
1464-5491
ISSN:
0742-3071
URN:
uuid:64a399ec-c7e6-4a9d-852a-e3ce456a01a7
Source identifiers:
2141
Local pid:
pubs:2141

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