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Journal article

Ciliary behaviour and mechano-transduction in the embryonic node: computational testing of hypotheses.

Abstract:

Left-right symmetry breaking in the mammalian embryo is believed to occur in a transient embryonic structure, the node: rotational motion of cilia within this structure creates a leftward flow of liquid that is the first asymmetric event observed. A hypothesis, often referred to as the "two-cilia" hypothesis, proposes that the node contains two kinds of primary cilia: motile cilia, driven by motor proteins, that rotate clockwise generating the leftward flow and passive cilia that act as mecha...

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Publication status:
Published

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Authors


Ventikos, Y More by this author
Journal:
Medical engineering and physics
Volume:
33
Issue:
7
Pages:
857-867
Publication date:
2011-09-05
DOI:
EISSN:
1873-4030
ISSN:
1350-4533
URN:
uuid:647ec1f2-105a-4dc9-a875-235dc71ae33e
Source identifiers:
103635
Local pid:
pubs:103635

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