- Abstract:
-
PURPOSE: The primary aim of this study was to measure the objective tumor response rate following treatment with indisulam [E7070; N-(3-chloro-7-indolyl)-1,4-benzenedisulfonamide] as second-line therapy in patients with advanced non-small cell lung cancer. The secondary aims were to determine progression-free survival, to assess the safety and tolerability of indisulam, and to study its pharmacokinetic and pharmacodynamic profile. EXPERIMENTAL DESIGN: Patients were randomized to receive indi...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1158/1078-0432.ccr-06-0249
-
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- Journal:
- Clinical cancer research : an official journal of the American Association for Cancer Research
- Volume:
- 13
- Issue:
- 6
- Pages:
- 1816-1822
- Publication date:
- 2007-03-05
- DOI:
- EISSN:
-
1557-3265
- ISSN:
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1078-0432
- URN:
-
uuid:6461964c-ab8e-4ee4-b4b5-6df208c5e5b8
- Source identifiers:
-
20791
- Local pid:
- pubs:20791
- Copyright date:
- 2007
Journal article
A randomized phase II pharmacokinetic and pharmacodynamic study of indisulam as second-line therapy in patients with advanced non-small cell lung cancer.
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