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Journal article

Short- and long-term glucocorticoid treatment enhances insulin signalling in human subcutaneous adipose tissue.

Abstract:

BACKGROUND: Endogenous or exogenous glucocorticoid (GC) excess (Cushing's syndrome) is characterized by increased adiposity and insulin resistance. Although GCs cause global insulin resistance in vivo, we have previously shown that GCs are able to augment insulin action in human adipose tissue, contrasting with their action in skeletal muscle. Cushing's syndrome develops following chronic GC exposure and, in addition, is a state of hyperinsulinemia. OBJECTIVES: We have therefore compared the ...

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Publication status:
Published

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Publisher copy:
10.1038/nutd.2010.3

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM
Role:
Author
Journal:
Nutrition and diabetes
Volume:
1
Issue:
1
Pages:
e3
Publication date:
2011-01-01
DOI:
EISSN:
2044-4052
ISSN:
2044-4052
URN:
uuid:644c62c5-ebf6-4182-be61-23bafa044dd3
Source identifiers:
482057
Local pid:
pubs:482057

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