Journal article
Tenascin-C increases lung metastasis by impacting blood vessel invasions
- Abstract:
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Metastasis is a major cause of death in cancer patients. The extracellular matrix molecule tenascin-C is a known promoter of metastasis, however the underlying mechanisms are not well understood. To further analyze the impact of tenascin-C on cancer progression we generated MMTV-NeuNT mice that develop spontaneous mammary tumors, on a tenascin-C knockout background. We also developed a syngeneic orthotopic model in which tumor cells derived from a MMTV-NeuNT tumor. Tumor cells were transfecte...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 6.6MB, Terms of use)
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- Publisher copy:
- 10.1016/j.matbio.2019.07.001
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Funding
Bibliographic Details
- Publisher:
- Elsevier
- Journal:
- Matrix Biology More from this journal
- Volume:
- 83
- Pages:
- 26-47
- Publication date:
- 2019-07-06
- Acceptance date:
- 2019-07-02
- DOI:
- EISSN:
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1569-1802
- ISSN:
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0945-053X
- Pmid:
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31288084
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:1035645
- UUID:
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uuid:6410b013-3185-4ea1-90fc-e1e661a72d1b
- Local pid:
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pubs:1035645
- Source identifiers:
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1035645
- Deposit date:
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2019-09-30
Terms of use
- Copyright holder:
- Sun et al.
- Copyright date:
- 2019
- Rights statement:
- © 2019 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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