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Thesis

Discovery of molecular signatures underlying angiogenic versus non angiogenic tumours

Abstract:

Angiogenesis has long been considered an essential prerequisite for tumour growth and progression. However, this understanding is being overturned by studies showing that many human tumours can metastasise without angiogenesis, suggesting that their microcirculation may be provided by non – sprouting vessels. Vessel co-option, a mechanism whereby tumour cells may incorporate and or migrate along pre-existing vessels presents an alternative mode of tumour blood supply. Vessel co-option...

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Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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