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Assessment of serum-free cortisol levels in patients with adrenocortical carcinoma treated with mitotane: a pilot study.

Abstract:

OBJECTIVE: Mitotane treatment in adrenocortical carcinoma (ACC) results in unreliable measurement of serum total cortisol (TC) levels because of an elevation in corticosteroid-binding globulin (CBG). DESIGN: The use of a newly-developed serum-free cortisol (FC) assay was assessed to investigate the characteristics of a more valid measure of cortisol status. PATIENTS: Sixty-two serum samples from patients with ACC treated with mitotane were studied. Different subgroups were studied according ...

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Publication status:
Published

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Journal:
Clinical endocrinology More from this journal
Volume:
72
Issue:
3
Pages:
305-311
Publication date:
2010-03-01
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
Language:
English
Keywords:
Pubs id:
pubs:138273
UUID:
uuid:63c98afe-fff0-43c5-8731-63803ead38bb
Local pid:
pubs:138273
Source identifiers:
138273
Deposit date:
2012-12-19

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