Journal article
The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria
- Abstract:
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A retrospective study of 261 Vietnamese adults with severe malaria was conducted to determine the relationship between cerebrospinal fluid (CSF) levels of metabolites of the kynurenine pathway, the incidence of neurologic complications, and the disease outcome. Three metabolites were measured: the excitotoxin quinolinic acid (QA); the protective receptor antagonist kynurenic acid (KA); and the proinflammatory mediator picolinic acid (PA). These measurements were related prospectively to CSF l...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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Authors
Funding
+ Lloyd's of London Tercentenary Foundation
More from this funder
Funding agency for:
Isabelle M. Medana
Bibliographic Details
- Publisher:
- University of Chicago Press Publisher's website
- Journal:
- The Journal of Infectious Diseases Journal website
- Volume:
- 185
- Issue:
- 5
- Pages:
- 650-656
- Publication date:
- 2002-03-05
- ISSN:
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0022-1899
- URN:
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uuid:63bd1d93-827b-4043-b214-0a3f6c98b4cc
- Local pid:
- ora:1440
Item Description
- Language:
- English
- Keywords:
- Subjects:
Terms of use
- Copyright holder:
- The Infectious Diseases Society of America
- Copyright date:
- 2002
- Notes:
- Citation: Medana, I. M. et al. (2002). 'The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria', The Journal of Infectious Diseases, 185(5), 650-656. [Available at http://www.journals.uchicago.edu/JID/].
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