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Cytogenetics of long-term survivors of ETV6-RUNX1 fusion positive acute lymphoblastic leukemia.

Abstract:

This study describes the cytogenetics of 33 children with ETV6-RUNX1 positive acute lymphoblastic leukemia (ALL) who had been in continuous complete remission for a minimum of 8.8 years [median event-free survival (EFS) 10.9 years]. The results were compared with a published series of 16 fusion positive patients treated on the same childhood ALL trial, who had relapsed (median EFS, 2.3 years). Interphase fluorescence in situ hybridization (FISH) at diagnosis showed deletion of the second ETV6...

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Publication status:
Published

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Publisher copy:
10.1002/gcc.20736

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Role:
Author
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Journal:
Genes, chromosomes and cancer
Volume:
49
Issue:
3
Pages:
253-259
Publication date:
2010-03-05
DOI:
EISSN:
1098-2264
ISSN:
1045-2257
URN:
uuid:63ae26e8-6862-4f96-a92b-baacc71b4fe9
Source identifiers:
48522
Local pid:
pubs:48522

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