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Comprehensive ascertainment of bleeding in patients prescribed different combinations of dual antiplatelet therapy (DAPT) and triple therapy (TT) in the UK: study protocol for three population-based cohort studies emulating ‘target trials’ (the ADAPTT Study)

Abstract:

Introduction

‘Real world’ bleeding in patients exposed to different regimens of dual antiplatelet therapy (DAPT) and triple therapy (TT, DAPT plus an anticoagulant) have a clinical and economic impact but have not been previously quantified.

Methods and analysis

We will use linked Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES) data to assemble populations eligible for three ‘target trials’ in patient groups: percutaneous coronary intervention (... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/bmjopen-2019-029388

Authors


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Role:
Author
ORCID:
0000-0002-1775-1949
More by this author
Role:
Author
ORCID:
0000-0001-8274-5580
Publisher:
BMJ Publishing Group
Journal:
BMJ Open More from this journal
Volume:
9
Article number:
e029388
Publication date:
2019-06-04
Acceptance date:
2019-03-04
DOI:
EISSN:
2044-6055
Pmid:
31167875
Language:
English
Pubs id:
pubs:1010621
UUID:
uuid:63a8a8c3-edc7-4eee-98e5-f828138678e5
Local pid:
pubs:1010621
Source identifiers:
1010621
Deposit date:
2019-08-19

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