- Abstract:
-
Radiation-induced damage to the genomic DNA of cells may lead to errors in transcription and replication and, if not repaired correctly, these may result in mutations, genomic instability and cell death. Laser microbeams have generally been used by many research groups to investigate the real-time dynamics of protein recruitment in response to DNA insults in mammalian cells; however, such irradiations induce a plethora of DNA damage (including UV base damage, base damage, SSBs and DSBs and...
Expand abstract - Funding agency for:
- Carlos Daniel Mendes de Oliveira Martins
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
- URN:
-
uuid:63a874a6-9348-4504-b4cd-b1cfd129b75d
- Local pid:
- ora:11728
- Language:
- English
- Keywords:
- Subjects:
- Copyright holder:
- Carlos Daniel Mendes de Oliveira Martins
- Copyright date:
- 2014
- Notes:
- This thesis is not currently available in ORA.
Thesis
Real-time studies of DNA repair kinetics following low-LET short-pulse electron radiation
Actions
Funding
+ Cancer Research UK; Medical Research Council
More from this funder
Bibliographic Details
Item Description
Terms of use
Metrics
Altmetrics
Dimensions
If you are the owner of this record, you can report an update to it here: Report update to this record