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Review: Does size matter? Placental debris and the pathophysiology of pre-eclampsia

Abstract:

A variety of 'debris' is shed from the syncytial surface of the human placenta ranging from large deported multinuclear fragments to sub-cellular components. It is increasingly clear that at least some of this material has signalling functions. Many categories of circulating debris are increased in pre-eclampsia, and exhibit proteins that are pro-inflammatory and could contribute to the systemic inflammatory response in normal pregnancy, which is exaggerated in pre-eclampsia. It is now eviden...

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Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
Journal:
Placenta More from this journal
Volume:
33
Issue:
SUPPL.
Publication date:
2012-02-01
DOI:
EISSN:
1532-3102
ISSN:
0143-4004
Language:
English
Keywords:
Pubs id:
pubs:313405
UUID:
uuid:6397fa8d-875e-4e15-bccb-8dfd14684cb5
Local pid:
pubs:313405
Source identifiers:
313405
Deposit date:
2013-11-16

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