- Abstract:
-
BACKGROUND: Rare mutations affecting the FOXP2 transcription factor cause a monogenic speech and language disorder. We hypothesized that neural pathways downstream of FOXP2 influence more common phenotypes, such as specific language impairment. METHODS: We performed genomic screening for regions bound by FOXP2 using chromatin immunoprecipitation, which led us to focus on one particular gene that was a strong candidate for involvement in language impairments. We then tested for associations be...
Expand abstract - Publication status:
- Published
- Journal:
- The New England journal of medicine
- Volume:
- 359
- Issue:
- 22
- Pages:
- 2337-2345
- Publication date:
- 2008-11-05
- DOI:
- EISSN:
-
1533-4406
- ISSN:
-
0028-4793
- URN:
-
uuid:63957647-9429-413e-8652-9124f3d86ff4
- Source identifiers:
-
34471
- Local pid:
- pubs:34471
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
A functional genetic link between distinct developmental language disorders.
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