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Journal article

THoR: a tool for domain discovery and curation of multiple alignments.

Abstract:
We describe a tool, THoR, that automatically creates and curates multiple sequence alignments representing protein domains. This exploits both PSI-BLAST and HMMER algorithms and provides an accurate and comprehensive alignment for any domain family. The entire process is designed for use via a web-browser, with simple links and cross-references to relevant information, to assist the assessment of biological significance. THoR has been benchmarked for accuracy using the SMART and pufferfish genome databases.

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Publisher copy:
10.1186/gb-2003-4-8-r52

Authors


Dickens, NJ More by this author
Ponting, CP More by this author
Journal:
Genome biology
Volume:
4
Issue:
8
Pages:
R52
Publication date:
2003
DOI:
EISSN:
1465-6914
ISSN:
1465-6906
URN:
uuid:6393fb95-5dc7-4186-89fc-7f8fd105bf25
Source identifiers:
238256
Local pid:
pubs:238256

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