The molecular pathogenesis of migraine: new developments and opportunities.

Journal article

Migraine is a prevalent, debilitating and costly disorder with an ongoing unmet medical need. Human genetic studies have provided considerable insights into the molecular underpinnings of this complex brain disorder. Classical linkage studies have revealed the causes of familial hemiplegic migraine, while more recently genome-wide association studies have identified several susceptibility loci for typical migraine. New ways of accessing neurons and other cells directly from patients with migr...

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Authors: Zameel Cader, M

• Publication status: Published
• Journal: Human molecular genetics
• Volume: 22
• Issue: R1
• Pages: R39-R44
• Publication date: 2013-10-01
• DOI: 10.1093/hmg/ddt364
• EISSN: 1460-2083
• ISSN: 0964-6906
• Language: English
• Keywords: Genetic Variation; Animals; Genetic Linkage; Migraine with Aura; Migraine Disorders; Genome-Wide Association Study; Genomics; Induced Pluripotent Stem Cells; Genetic Predisposition to Disease; Humans