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Recognition molecules myelin-associated glycoprotein and tenascin-C inhibit integrin-mediated adhesion of neural cells to collagen.

Abstract:

Because of the importance of collagens in mediating cell-substrate interactions and the association of collagens with neural recognition molecules in the peripheral nervous system, the ability of neural recognition molecules to modify the substrate properties of collagens, in particular collagen type I, for cell adhesion was determined. Two cell lines, the N2A neuroblastoma and PC12 pheochromocytoma, were investigated for their capacity to adhere to different collagen types in the absence or ...

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Publication status:
Published

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Publisher copy:
10.1002/jnr.490400405

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Conscience, JF More by this author
Probstmeier, R More by this author
Carbonetto, S More by this author
Schachner, M More by this author
Journal:
Journal of neuroscience research
Volume:
40
Issue:
4
Pages:
458-470
Publication date:
1995-03-05
DOI:
EISSN:
1097-4547
ISSN:
0360-4012
URN:
uuid:636f706d-e17c-48a3-869f-d7577e4ff164
Source identifiers:
469747
Local pid:
pubs:469747

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