- Abstract:
-
Although genes, protein aggregates, environmental toxins, and other factors associated with Parkinson's disease (PD) are widely distributed in the nervous system and affect many classes of neurons, a consistent feature of PD is the exceptional and selective vulnerability of dopamine (DA) neurons of the SNc. What is it about these neurons, among all other neurons in the brain, that makes them so susceptible in PD? We hypothesize that a major contributory factor is the unique cellular architect...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/mds.25135
-
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- Journal:
- Movement disorders : official journal of the Movement Disorder Society
- Volume:
- 27
- Issue:
- 12
- Pages:
- 1478-1483
- Publication date:
- 2012-10-05
- DOI:
- EISSN:
-
1531-8257
- ISSN:
-
0885-3185
- URN:
-
uuid:636a040d-3c78-4be9-94b6-768219acab52
- Source identifiers:
-
375287
- Local pid:
- pubs:375287
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Living on the edge with too many mouths to feed: why dopamine neurons die.
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