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Journal article

Distal transcript of the dystrophin gene initiated from an alternative first exon and encoding a 75-kDa protein widely distributed in nonmuscle tissues.

Abstract:

A transcript generated by the distal part of the Duchenne Muscular Dystrophy (DMD) gene was initially detected in cells where the full size 14-kilobase (kb) messenger RNA is not found at a significant level. This transcript, approximately 4.5 kb long, corresponds to the cysteine-rich and carboxyl-terminal domains of dystrophin. It begins with a novel 80- to 100-nucleotide exon containing an ATG start site for a new coding sequence of 17 nucleotides in-frame with the consecutive dystrophin cDN...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.89.16.7506

Authors


Hugnot, JP More by this author
Gilgenkrantz, H More by this author
Vincent, N More by this author
Morris, GE More by this author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
89
Issue:
16
Pages:
7506-7510
Publication date:
1992-08-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:6368123b-755a-4579-bfbc-96dc0af022af
Source identifiers:
43866
Local pid:
pubs:43866

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