Journal article
Phenotypic and transcriptomic characterization of canine myeloid-derived suppressor cells
- Abstract:
-
Myeloid-derived suppressor cells (MDSCs) are key players in immune evasion, tumor progression and metastasis. MDSCs accumulate under various pathological states and fall into two functionally and phenotypically distinct subsets that have been identified in humans and mice: polymorphonuclear (PMN)-MDSCs and monocytic (M)-MDSCs. As dogs are an excellent model for human tumor development and progression, we set out to identify PMN-MDSCs and M-MDSCs in clinical canine oncology patients. Canine hy...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Nature Research Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 9
- Issue:
- 2019
- Article number:
- 3574
- Publication date:
- 2019-03-05
- Acceptance date:
- 2019-02-13
- DOI:
- EISSN:
-
2045-2322
- ISSN:
-
2045-2322
- Pmid:
-
30837603
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:980549
- UUID:
-
uuid:635879bb-eef3-4d4b-9fcf-ed2779781d44
- Local pid:
- pubs:980549
- Source identifiers:
-
980549
- Deposit date:
- 2019-04-04
Terms of use
- Copyright holder:
- Goulart et al.
- Copyright date:
- 2019
- Rights statement:
- © The Authors. This article is licensed under a Creative Commons Attribution 4.0 International License
- Licence:
- CC Attribution (CC BY)
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