Journal article
The long non-coding RNA Dali is an epigenetic regulator of neural differentiation
- Abstract:
-
Many intergenic long noncoding RNA (lncRNA) loci regulate the expression of adjacent protein coding genes. Less clear is whether intergenic lncRNAs commonly regulate transcription by modulating chromatin at genomically distant loci. Here, we report both genomically local and distal RNA-dependent roles of Dali, a conserved central nervous system expressed intergenic lncRNA. Dali is transcribed downstream of the Pou3f3 transcription factor gene and its depletion disrupts the differentiation of ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- eLife Sciences Publications Publisher's website
- Journal:
- eLife Journal website
- Volume:
- 2014
- Issue:
- 3
- Article number:
- e04530
- Publication date:
- 2014-11-21
- Acceptance date:
- 2014-11-21
- DOI:
- EISSN:
-
2050-084X
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:63427120-4b60-47a4-9440-a79bc430728e
- Local pid:
- pubs:491686
- Source identifiers:
-
491686
- Deposit date:
- 2014-12-14
Terms of use
- Copyright holder:
- Chalei et al
- Copyright date:
- 2014
- Notes:
- © 2014, Chalei et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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