- Abstract:
-
There is increasing evidence that hypoxia-regulated gene expression influences tumor aggressiveness, contributing to the poorer outcome of patients with hypoxic tumors. The role of the transcriptional complex hypoxia-inducible factor-1 as an important mediator of hypoxia-regulated gene expression is one of the best documented pathways. Recently, it has emerged that certain tumor-associated carbonic anhydrases (CAs) can be added to the list of known hypoxia-inducible factor-responsive genes. H...
Expand abstract - Publication status:
- Published
- Journal:
- Cancer research
- Volume:
- 61
- Issue:
- 17
- Pages:
- 6394-6399
- Publication date:
- 2001-09-05
- EISSN:
-
1538-7445
- ISSN:
-
0008-5472
- URN:
-
uuid:6341cb55-fe26-49f5-9594-9b0564b525ec
- Source identifiers:
-
74281
- Local pid:
- pubs:74281
- Language:
- English
- Keywords:
- Copyright date:
- 2001
Journal article
Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix.
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