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Journal article

Subcutaneous adipose tissue from obese and lean adults does not release hepcidin in vivo.

Abstract:

Hepcidin is the main regulator of systemic iron homeostasis and is primarily produced by the liver but is also expressed, at the mRNA-level, in periphery tissues including the subcutaneous and visceral adipose tissue. Obesity is associated with elevated hepcidin concentrations and iron depletion suggesting that the exaggerated fat mass in obesity could contribute significantly to circulating hepcidin levels consequently altering iron homeostasis. The objective of this study was to determine i...

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Publication status:
Published

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Publisher copy:
10.1100/2011/634861

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
TheScientificWorldJournal More from this journal
Volume:
11
Pages:
2197-2206
Publication date:
2011-01-01
DOI:
EISSN:
1537-744X
ISSN:
2356-6140
Language:
English
Keywords:
Pubs id:
pubs:216383
UUID:
uuid:633e28a3-5403-4bc6-baa5-eb91842429c6
Local pid:
pubs:216383
Source identifiers:
216383
Deposit date:
2012-12-19

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