Journal article icon

Journal article

Critical influence of natural regulatory CD25+ T cells on the fate of allografts in the absence of immunosuppression.

Abstract:

BACKGROUND: Allografts are occasionally accepted in the absence of immunosuppression. Because naturally occurring CD4(+)CD25(+) regulatory T cells (natural CD25(+) Treg cells) have been shown to inhibit allograft rejection, we investigated their influence on the outcome of allografts in nonimmunosuppressed mouse recipients. METHODS: We compared survival times of male CBA/Ca skin grafts in female CBA/Ca recipients expressing a transgenic anti-HY T-cell receptor on a RAG-1(+/+) (A1[M]RAG+) or ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Benghiat, FS More by this author
Detienne, S More by this author
Expand authors...
Journal:
Transplantation
Volume:
79
Issue:
6
Pages:
648-654
Publication date:
2005-03-05
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
URN:
uuid:632c8cac-d030-4aa7-8336-1a4c06031a48
Source identifiers:
4924
Local pid:
pubs:4924

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP