- Abstract:
-
Whether the number of concurrent clones in asymptomatic Plasmodium falciparum infections reflects the degree of host protection was investigated in children living in areas with different levels of transmission on the coast of Kenya. The number of concurrent clones was determined on the basis of polymorphism in msp2, which encodes the vaccine candidate antigen merozoite surface protein 2. In a low-transmission area, most children had monoclonal infections, and diversity did not predict a risk...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1086/605652
-
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- Journal:
- The Journal of infectious diseases
- Volume:
- 200
- Issue:
- 7
- Pages:
- 1166-1175
- Publication date:
- 2009-10-05
- DOI:
- EISSN:
-
1537-6613
- ISSN:
-
0022-1899
- URN:
-
uuid:63287ed8-f188-4f4d-a803-ca5669407904
- Source identifiers:
-
41346
- Local pid:
- pubs:41346
- Copyright date:
- 2009
Journal article
Transmission-dependent tolerance to multiclonal Plasmodium falciparum infection.
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