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Characterization of the putative operon containing arylamine N-acetyltransferase (nat) in Mycobacterium bovis BCG.

Abstract:

Mycobacterium bovis BCG and Mycobacterium tuberculosis possess a single arylamine N-acetyltransferase whose gene is predicted to occur within a six-gene operon. Deletion of the nat gene caused an extended lag phase in M. bovis BCG and a cell morphology associated with an altered pattern of cell wall mycolates. Analysis of cDNA from M. bovis BCG shows that during in vitro growth all the genes in the putative nat operon are expressed and the open reading frames are contiguous, supporting the ex...

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Publication status:
Published

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Journal:
Molecular microbiology More from this journal
Volume:
59
Issue:
1
Pages:
181-192
Publication date:
2006-01-01
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
Language:
English
Keywords:
Pubs id:
pubs:328359
UUID:
uuid:632763b9-b94b-405b-bcd2-b519062dd2af
Local pid:
pubs:328359
Source identifiers:
328359
Deposit date:
2013-11-17

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