The use of small interfering RNAs (siRNAs) to induce gene silencing has opened a new avenue in drug discovery. However, their therapeutic potential is hampered by inadequate tissue-specific delivery. Exosomes are promising tools for drug delivery across different biological barriers. Here we show how exosomes derived from cultured cells can be harnessed for delivery of siRNA in vitro and in vivo. This protocol first describes the generation of targeted exosomes through transfection of an expr...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Exosome-mediated delivery of siRNA in vitro and in vivo.
If you are the owner of this record, you can report an update to it here: Report update to this record