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Synthesis of glycoproteins.

Abstract:
The remarkable diversity of techniques available for the construction of glycoproteins is presented. The complexity of synthesis is still an issue but by judicious and combined use of some of the complementary techniques, practical synthesis of complex glycoproteins will be achieved. Since glycosylation has an important role in correct protein folding, it is unlikely to be enough to "just make it", and in this regard the timing of glycosylation and assembly strategy in any synthesis may too become a vital issue.
Publication status:
Published

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Publisher copy:
10.1021/cr0004310

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Chemical reviews
Volume:
102
Issue:
2
Pages:
579-602
Publication date:
2002-02-01
DOI:
EISSN:
1520-6890
ISSN:
0009-2665
Source identifiers:
38195
Language:
English
Keywords:
Pubs id:
pubs:38195
UUID:
uuid:630dcf55-0a66-45d7-8d38-2f194030c769
Local pid:
pubs:38195
Deposit date:
2012-12-19

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