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Fueling open innovation for malaria transmission-blocking drugs: hundreds of molecules targeting early parasite mosquito stages

Abstract:

Background:Despite recent successes at controlling malaria, progress has stalled with an estimated 219 million cases and 435,000 deaths in 2017 alone. Combined with emerging resistance to front line antimalarial therapies in Southeast Asia, there is an urgent need for new treatment options and novel approaches to halt the spread of malaria. Plasmodium, the parasite responsible for malaria propagates through mosquito transmission. This imposes an acute bottleneck on the parasite population and...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fmicb.2019.02134

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Microbiology Journal website
Volume:
10
Article number:
2134
Publication date:
2019-09-13
Acceptance date:
2019-08-30
DOI:
EISSN:
1664-302X
Pmid:
31572339
Language:
English
Keywords:
Pubs id:
pubs:1062569
UUID:
uuid:630bed50-85ce-41cb-ab52-4e977c01d84d
Local pid:
pubs:1062569
Source identifiers:
1062569
Deposit date:
2019-10-16

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