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Influence of collagenase loading on long-term preservation of pig pancreas by the two-layer method for subsequent islet isolation.

Abstract:

BACKGROUND: The introduction of the two-layer method (TLM) for long-term human pancreas preservation revealed the enormous potential of TLM to improve graft function of isolated islets. It is still unclear whether pig islets can be successfully isolated from pancreases after prolonged cold ischemia. To clarify this question, pig pancreases were subjected to 7-hour preservation by University of Wisconsin solution (UWS) storage or TLM. Another aim was to verify whether TLM can be synergistical...

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
Transplantation More from this journal
Volume:
79
Issue:
1
Pages:
38-43
Publication date:
2005-01-01
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
Language:
English
Keywords:
Pubs id:
pubs:268959
UUID:
uuid:6304fecd-feac-44ef-a4f3-a93fcf5de138
Local pid:
pubs:268959
Source identifiers:
268959
Deposit date:
2012-12-19

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