Journal article
Identifying the immune interactions underlying HLA class I disease associations
- Abstract:
-
Variation in the risk and severity of many autoimmune diseases, malignancies and infections is strongly associated with polymorphisms at the HLA class I loci. These genetic associations provide a powerful opportunity for understanding the etiology of human disease. HLA class I associations are often interpreted in the light of ‘protective’ or ‘detrimental’ CD8+ T cell responses which are restricted by the host HLA class I allotype. However, given the diverse receptors which are bound by HLA c...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Medical Research Council
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Bibliographic Details
- Publisher:
- eLife Sciences Publications Publisher's website
- Journal:
- eLife Journal website
- Volume:
- 9
- Article number:
- e54558
- Publication date:
- 2020-05-27
- Acceptance date:
- 2020-03-06
- DOI:
- EISSN:
-
2050-084X
- Pmid:
-
32238263
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1107399
- Local pid:
- pubs:1107399
- Deposit date:
- 2021-01-21
Terms of use
- Copyright date:
- 2020
- Rights statement:
- This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.
- Licence:
- CC Public Domain Dedication (CC0)
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