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Journal article

Autoantibodies to GAD65 and IA-2 in canine diabetes mellitus.

Abstract:

Diabetes mellitus in dogs shares many characteristics with the human type 1 disease and virtually all diabetic dogs require insulin therapy to control hyperglycaemia. Insulin deficiency is suspected to result from immune-mediated destruction of pancreatic beta cells in some cases. Human patients suffering from Type 1A (immune-mediated) diabetes or latent autoimmune diabetes of the adult (LADA) demonstrate circulating autoantibodies against the 65kDa isoform of glutamic acid decarboxylase (GAD...

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Publication status:
Published

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Journal:
Veterinary immunology and immunopathology
Volume:
126
Issue:
1-2
Pages:
83-90
Publication date:
2008-11-05
DOI:
EISSN:
1873-2534
ISSN:
0165-2427
URN:
uuid:62ede5c9-3831-46bb-91bb-07e09084c6dc
Source identifiers:
445317
Local pid:
pubs:445317

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