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Microbe Profile: dictyostelium discoideum: model system for development, chemotaxis and biomedical research

Abstract:
The social amoeba Dictyostelium discoideum is a versatile organism that is unusual in alternating between single-celled and multi-celled forms. It possesses highly-developed systems for cell motility and chemotaxis, phagocytosis, and developmental pattern formation. As a soil amoeba growing on microorganisms, it is exposed to many potential pathogens; it thus provides fruitful ways of investigating host-pathogen interactions and is emerging as an influential model for biomedical research.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1099/mic.0.001040

Authors


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Institution:
University of Oxford
Division:
MSD
Sub department:
Biochemistry
Role:
Author
More from this funder
Name:
National Centre for the Replacement, Refinement and Reduction of Animals in research (NC3RS)
Grant:
NC/M000834/1
More from this funder
Name:
E P A Cephalosporin Fund
Grant:
CF 302
CF 331
Publisher:
Microbiology Society
Journal:
Microbiology More from this journal
Volume:
167
Issue:
3
Article number:
001040
Publication date:
2021-03-01
Acceptance date:
2021-02-09
DOI:
EISSN:
1465-2080
ISSN:
1350-0872
Language:
English
Keywords:
Pubs id:
1160440
Local pid:
pubs:1160440
Deposit date:
2021-02-09

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