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Journal article

Relationship between novel isoforms, functionally important domains, and subcellular distribution of CD164/endolyn

Abstract:

Functional analyses have indicated that the human CD164 sialomucin may play a key role in hematopoiesis by facilitating the adhesion of human CD34+cells to the stroma and by negatively regulating CD34+CD38lo/− cell proliferation. We have identified three novel human CD164 variants derived by alternative splicing of bona fide exons from a single genomic transcription unit. The predominant CD164(E1–6) isoform, encoded by six exons, is a type I transmembrane protein containing two extracellular ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1074/jbc.M007965200

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
Publisher:
American Society for Biochemistry and Molecular Biology
Journal:
Journal of Biological Chemistry More from this journal
Volume:
276
Pages:
2139-2152
Publication date:
2000-10-10
Acceptance date:
2000-10-06
DOI:
EISSN:
1083-351X
ISSN:
0021-9258
Pubs id:
pubs:344464
UUID:
uuid:62d30d8a-5b04-4f8d-bf6e-bc846ae08684
Local pid:
pubs:344464
Source identifiers:
344464
Deposit date:
2016-03-04

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