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Increased cortical inhibition in depression: a prolonged silent period with transcranial magnetic stimulation (TMS).

Abstract:

BACKGROUND: Motor slowing in depression may be associated with a relative dopaminergic (DA) deficit. Bradykinesia in Parkinson's syndrome is associated with an abnormally short silent period (SP) using transcranial magnetic stimulation (TMS). We hypothesized that depression would also be associated with a short SP. METHODS: Sixteen patients with DSM-IV depression and 19 matched controls participated. SPs were elicited by exercising the contralateral abductor policis brevis (APB) during TMS. R...

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Publication status:
Published

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Publisher copy:
10.1017/s0033291799002032

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
Journal:
Psychological medicine
Volume:
30
Issue:
3
Pages:
565-570
Publication date:
2000-05-01
DOI:
EISSN:
1469-8978
ISSN:
0033-2917
Source identifiers:
139167
Language:
English
Keywords:
Pubs id:
pubs:139167
UUID:
uuid:62cd1b67-469e-4368-a1b4-1253d626d103
Local pid:
pubs:139167
Deposit date:
2012-12-19

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